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About CBD

What is hemp?

There are many different varieties of the cannabis plant. “Hemp” refers to the non-psychoactive varieties of the Cannabis Sativa L plant. Both hemp and marijuana come from the same cannabis species, but are genetically different and can be further differentiated by cultivation methods, intended use and chemical makeup.

Hemp oil is retrieved from the stalk, seed, and flowers of hemp plants. Hemp oil is a natural concentrate extracted from cannabis plants that are high in cannabidiol (CBD) and low in tetrahydrocannabinol (THC). Because CBD, unlike THC, is non-psychoactive, hemp does not cause a euphoric high.

In addition to its main cannabinoid, CBD, hemp oil contains trace amounts of over 100 other phytocannabinoids, including cannabichromene (CBC), cannabigerol (CBG), cannabinol (CBN) and cannabidivarian (CBDV). Hemp oil also contains nutritious material such as omega-3 fatty acids, terpenes, vitamins, chlorophyll, and amino acids.

The synergistic blend of ingredients found in this nutritional supplement work with the body’s own endocannabinoid system, which manages a variety of biological processes like appetite, sleep, relaxation, and inflammation responses.

By communicating with CB1 and CB2, endocannabinoid receptors which are found throughout the brain and body, hemp oil assists the endocannabinoid system in the regulation of homeostasis, the body’s natural state of balance.

What is the endocannabinoid system?

The endocannabinoid system, or ECS, is an integral part of our physiology as humans. It helps us maintain homeostasis, or balance, in our bodies by communicating with other biological systems.

The ECS has beneficial effects on many physical conditions because of its unique communication method (which we’ll get to later). These beneficial effects can be placed in two categories: the first is to help the body heal itself in the face of injury and disease, and the second is to modulate pleasure, energy and well-being. If the endocannabinoid system remains strong, it can help other systems stay healthy, fight disease and communicate smoothly.

The endocannabinoid system was discovered in the mid-1990s by Israeli researcher Dr. Raphael Mechoulam. Dr. Mechoulam’s world-changing research discovered two main receptors, CB1 and CB2. Since that pivotal moment, there has been a substantial amount of research done to understand just how the ECS works. While it’s quite complex, the Endocannabinoid System can be grouped into three main parts:

  • Internally produced endocannabinoids – called Anandamide and 2-AG
  • Receptors that receive their signals – called CB1 and CB2
  • Enzymes that build and recycle these endocannabinoids

The ECS operates through what is known as retrograde signaling. While most other biological systems send their chemical signals from presynaptic (sending) nerves to postsynaptic (receiving) nerves, endocannabinoids travel backwards across the nerve synapse. This unique quality allows endocannabinoids, which can be found throughout the body, to modulate the sending of other signals on demand.

In other words, every part of the body is producing cannabis-like compounds, all the time, and these compounds are being used to balance out biological function! This reality, which was discovered not much more than twenty years ago, has huge health implications.

In an ideal world, the ECS would function perfectly. Our endocannabinoids would be produced in accordance with their receptor’s demands, and receptors would maintain sensitivity in the areas needed most, retaining their ability to maintain homeostasis.

Like anything else in the body, though, the ECS can develop imbalances of its own. Enzymes may not produce enough endocannabinoids, or they may break down existing cannabinoids too quickly. When the endocannabinoid system becomes imbalanced, its regulatory ability is dampened and widespread dysregulation can result. This loss of control, in turn, can present itself as many of the chronic diseases we are familiar with today.

This is where the importance of Hemp comes in. It’s CBD component gently regulates the Endocannabinoid System through a variety of mechanisms – including balancing out ECS enzymes and allowing endocannabinoids like anandamide to remain active where they’re needed.  By communicating with the Endocannabinoid System’s CB1 and CB2 receptors, hemp oil and its CBD component assist the Endocannabinoid System in maintaining homeostasis.

Is hemp safe?

Yes, hemp is safe.

It contains less than 1% of naturally occurring THC, the phytochemical responsible for the “high” commonly observed with marijuana.

THC has been researched extensively, and science shows us that combining it with much larger amounts of CBD, as seen in the hemp plant, aids the body in maintaining endocannabinoid system health.

Unlike marijuana, which contains at least 5–10 % THC and often more, hemp and hemp oil products contain less than 1% THC. This low amount of THC means that consuming hemp in any of its forms provides health and healing benefits without the high.

Does CBD from hemp oil work?


In addition to its main cannabinoid, CBD, hemp oil contains trace amounts of over 100 other phytocannabinoids, including cannabichromene (CBC), cannabigerol (CBG), cannabinol (CBN) and cannabidivarin (CBDV). Hemp oil also contains other nutritious material such as omega-3 fatty acids, terpenes, flavonoids, vitamins, chlorophyll, and amino acids. CBD itself is a very potent anti-oxidant that fights age-related diseases.

The synergistic blend of ingredients found in hemp work with the body’s own endocannabinoid system, which manages a variety of biological processes like appetite, sleep, relaxation, and inflammation responses. By communicating with CB1 and CB2, endocannabinoid receptors which are found throughout the brain and body, hemp oil assists the endocannabinoid system in the regulation of homeostasis, the body’s natural state of balance.

Hemp can also relieve chronic pain by helping our other biological systems reduce inflammation.  Over time, an overabundance of inflammation can lead to tissue damage and pain. To dull this pain, many people rely on highly addictive prescription pain medications. However, long term usage of prescription medications can have negative effects on the kidneys, stomach, and liver. Hemp oil is known for its natural anti-inflammatory properties and does not have any harsh side effects.

Hemp Oil Can Help Manage:

  • Arthritis
  • Cancer
  • Diabetes
  • PTSD
  • Anxiety
  • Depression
  • OCD
  • Autism
  • Insomnia
  • Alcoholism
  • Epilepsy
  • Neurological Disorders

And much, much more! The widespread benefits of hemp oil are made possible by the unique way that the endocannabinoid system mediates so many other systems in our bodies. Once again, all of this can be achieved without lethargy, euphoria or mind-altering effects.

Hemp is one of the healthiest plants in the world. If you are in chronic pain and tired of trying “quick fixes” to no avail, then hemp oil might be your best bet to soothe your pain and help your body heal itself.

Is CBD fast acting or does it take a while to build in your system?

CBD oil takes a few weeks to really start working for you. During that time, your body is building more endocannabinoid receptors so that you can become more receptive to CBD. The CBD oil also needs time to reach a steady therapeutic level.

Dosing and Effects

How much should I take?

Please look at the comprehensive delivery methods and dosage section on this website.

Is CBD safe to take with my current medications?

In most cases. CBD should be taken several hours apart from your other prescribed medications because CBD can interfere with how medications are metabolized. Blood thinner medications and blood pressure medications in particular should be taken apart from your CBD oil. However opiate medication can be taken together with CBD oil as CBD enhances the pain relieving qualities of opiate medications, without feel high. Over time, you will be able to take less opiate pain medication.

How do I know that I need to take a break from CBD oil?

People who take high doses of CBD oil (50 mg or more/day) may need to “reset” for a day or two. Some people may experience a return of symptoms which appears to them as if the CBD oil is no longer as effective. If they abstain from the CBD oil for 24-48 hours, their endocannabinoid receptors become more sensitive again to the effects of the CBD, and the CBD oil will once again become effective for them.

Is it ok to take for a prolonged period of time?

Yes, CBD oil can be taken for long periods of time without causing any ill effects on your health.

Can you overdose?

No, you cannot overdose from CBD oil. The only side effect you might experience would be drowsiness.

Are there side effects to CBD oil?

Side effects we have noticed from some of our patients include headaches and nausea. Some people have also noticed that CBD can act as an appetite stimulant. For more complete information, please look at the Side Effects and Drug Interactions section of our site.


Will the CBD oil get me high?

No, CBD oil will not get you high as CBD is not psychoactive, nor is the trace amount (0.3 % or less) of THC in the full spectrum variety of CBD oil strong enough to get you high.

Is hemp legal?

Hemp is legal as a supplement product as long as it contains less than 0.3% THC. However, CBD sourced from hemp is not legal in all 50 states at this time. At this time (Sept. 2018), California, Ohio and Massachusetts have passed legislation to prevent the sale of hemp-derived CBD products in their states.

How is it different than marijuana?

Hemp is not marijuana.

There are different varieties of the cannabis plant. Hemp refers to the non-psychoactive varieties of the Cannabis Sativa L plant. Both hemp and marijuana are members of the same cannabis species, but are genetically different. Hemp contains only about 0.3% – 1% THC (tetrahydrocannabinol, the phytochemical that produces a euphoric high) while marijuana contains at least 5% – 10%  THC.

Hemp and marijuana, which also have different leaf patterns, can be further differentiated by use (hemp is more commonly used for medicinal and industrial purposes) and cultivation methods.

Is there THC in CBD oil?

CBD oil can either be “full spectrum” or an isolate. A trace amount, less than 0.3% THC, is present in the full spectrum variety of CBD oil. This small amount WILL NOT get you high. The isolate version of CBD only contains the CBD molecule. It has no other types of phytocannabinoids in this CBD oil, including THC.

If CBD is so great, why is it banned for our military/government employees?

Government and military employees cannot take CBD products because CBD is still listed as an illegal, schedule 1 substance according to the DEA. At the state level, however, CBD is legal for civilians. Recently the DEA and FDA made a change in how they schedule CBD for a specific CBD-derived drug for specific epilepsy syndromes. You can read a statement about this change from our CEO by clicking here.


What is the best way to consume CBD products?

Please read the comprehensive delivery methods and dosage section on this website.

Do I need to tell my primary care physician that I am taking hemp?

Yes, you do. Your doctor needs to know about ALL supplements you are currently taking so your PCP can find any possible interactions with your prescribed medications, and also to determine if you need to space taking your CBD oil apart from when you take other prescribed medicines.

How do I store CDB oil?

Store the CBD oil up in a high place at room temperature, such as a bathroom or kitchen cabinet, away from children.

What is in your CBD oil?

Integrated Hemp Solutions’ CBD oil contains all of the phytocannabinoids such as CBG, CBD, and THC in it. However, the THC content is less than 0.3%. We use hemp oil and grape seed oil as the carrier oils for our CBD oil products.

Can you mix it with food? If so, what type of food?

CBD oil can be mixed with any food. It is recommended that the CBD oil be mixed with soft food like yogurt or applesauce in a spoon to be taken by mouth. It is not recommended to put CBD oil into food that is spread across a plate because you cannot determine if you have taken a full dose of CBD once it is mixed into the food on your plate.

Can the CBD oil be mixed with a topical cream? How much?

CBD oil can be mixed with a topical cream or oil such as almond oil or coconut oil. At least 8 mg of CBD oil should be mixed with the cream or oil to feel an effect.

What does it taste/smell like?

CBD oil may have an earthy and herbal smell and taste.

Will my insurance cover CBD?

In the state of North Carolina, a neurologist can prescribe CBD oil for epilepsy. This instance is the only way CBD oil would be covered by insurance in North Carolina.

When will I get my order?
Orders placed before 4:00 pm EST usually ship out the same day from Southern Pines, NC. Depending on your location, it may take anywhere from 2 – 4 day to get to you. You will get a confirmation email with tracking number when the order is shipped.
Can I return my order?
We strive for 100% customer satisfaction guarantee and are happy to offer a returns for unopened bottles within 30 day of purchase. If you have question on dosage or use please call our customer service number of nurse line.


Will I be able to reduce my dependence on pain medication?

When you begin to consume CBD oil with your prescribed pain medications, you will notice that feel better pain relief without feeling high. CBD oil is best taken together with your pain medications. Over time, you will be able to reduce your pain medications because of the synergistic effect CBD oil has when combined with them reduces inflammation – one of the main causes of pain – throughout your body.

Can it help with anxiety and depression? If so, how?

Yes, CBD oil can help with anxiety and depression. CBD activates the serotonin receptors and produces anti-anxiety effects. CBD also stimulates the release of dopamine that helps alleviate the symptoms of depression.

Can the CBD oil help to release tension in muscles?

Yes, CBD oil can relieve muscle spasms and decrease pain overall in the body.

Does CBD oil affect your sex drive?

No, it does not affect your sex drive.